Philosophical Vegan Forum

The results of the study suggest that loss of iodine through profuse sweating may lead to iodine deficiency...
—Electrolyte loss in sweat and iodine deficiency in a hot environment

We conclude that in areas of iodine deficiency in which millet is a major component of the diet, its ingestion may contribute to the genesis of endemic goiter.
—Antithyroid and goitrogenic effects of millet

Excess dietary iodine: In genetically susceptible individuals, increased consumption of Iodine can act as a trigger for thyroiditis.
Dietary Factors... Various Possible Toxicants Involved in Thyroid Dysfunction: A Review

Conclusion
The benefits of iodine repletion outweigh the risk of thyroid auto-immunity, hence global iodine sufficiency should be ensured.

Iodine deficiency is the world's single greatest cause of preventable mental retardation. It is especially damaging during the early stages of pregnancy and in early childhood. —Household use of iodized salt in rural area

A review of case reports show that iodine intake of less than 1000 mcg/day is safe for most people.—Iodised salt is safe

Losses during boiling, roasting, deep frying and microwave cooking were found to be 40.23%, 10.57%, 10.40% and 27.13% respectively. From the obtained results, authors have concluded that the loss of iodine depends upon type of cooking method and time of addition of salt during cooking.

Thus, to prevent iodine losses while cooking, it is advisable to sprinkle salt on food after cooking (wherever possible) rather than adding salt while cooking as is done traditionally in India. Further, storage of salt in hot and humid condition near the cooking area should be avoided.
—Effect of different cooking methods on iodine losses

Jebus wrote: ↑Tue Aug 28, 2018 9:51 pm I put about a third of a teaspoon of iodized salt in my nut mix.

Oral administration of concentrated salt solutions causes irritation of the orogastric mucosa.

The GI effects of oral salt administration include swollen tongue, nausea, vomiting, diarrhea, abdominal cramps, and thirst.

Hypertonic salt solutions can produce ... a distinctive microscopic lesion of the kidney ... parenchymatous dehydration produces a shrinking which is most conspicuous in the convoluted tubules of the renal cortex. Some experimental evidence suggests that similar hypernatremic syndromes may be produced with normal salt diets if water intake is restricted.

Sodium chloride at concentrations much above that in tears causes a stinging sensation on contact with the eye. Solutions up to 10% do not alter the permeability of the corneal epithelium, but solutions more dilute than 0.9% sodium chloride cause increased permeability.

A surprisingly small amount of salt intake can result in a fatal outcome. We report two cases of severe salt intoxication in two girls, aged 20 and 7 months, who presented with severe hypernatremia. Both had seizures after accidental salt ingestion. In the first case, salt instead of sugar was inadvertently added to two yogurts, leading to hypernatremia and convulsions. In the second case, a mistake in the preparation of salt-saturated water as an oral rehydration solution provoked seizures, coagulopathy and longitudinal venous sinus thrombosis. Both cases developed encephalic death.

SIGNS AND SYMPTOMS/ Fatal salt poisoning has occurred in children following the inadvertent substitution of table salt for sugar in infant formulas and the administration of salt as an emetic. Symptoms are generally seen within hours of oral ingestion and include seizures, obtundation, coma, and cardiorespiratory arrest. Serum sodium levels may be greater than 180 mEq/L. Such high levels of sodium create a large osmotic gradient between the extracellular fluid (ECF) and Intracellular fluid (ICF), leading to extreme cellular dehydration and brain injury. Autopsy studies of children dying from salt poisoning have shown capillary and venous congestion of the central nervous system, subarachnoid and parenchymal hemorrhage, and dural sinus occlusion.

An estimated dose of more than 400 mEq/kg resulted in brain injury and death in a 2 year old child given a salt water solution to induce emesis.

Although a plethora of reports on life-threatening complications of salt emesis has been published since the early 1960s, salt is still used to induce emesis in cases of intoxication in the clinical as well as in the domestic setting.

The case of a 63-year-old female nursing home inhabitant who accidentally ingested the anti-epileptic medication of another nursing home inhabitant is described. After telephone instructions from a specialist in internal medicine, caregivers forced the woman to vomit by means of saline solution and digital manipulation. This caused not only substantial hypernatriemia but also aspiration pneumonia, from which the woman died after short hospitalization. The potential toxicity by major electrolyte shifts in terms of hypernatriemia following administration of sodium chloride solution is well known; this measure is medically contraindicated for the induction of vomiting.

Saturated solutions of kitchen salt have been used by paramedics to provoke vomiting in two patients: a 50-years-old woman and a 44-years-old man. According to anamnesis patients received respectively around 330 and 500 g of dissolved kitchen salt. In both cases bloody emesis and bloody diarrhea, alteration of consciousness and low blood pressure were noted. Maximum blood sodium level was 177 and 173 mmol/L respectively. Due to signs of gastrointestinal bleeding gastric endoscopy was performed in both cases, which demonstrated widespread damage of gastric mucosa. Normalization of electrolyte disturbances and improvement of patients' status was achieved with intravenous infusion of 5% glucose. Both patients have been discharged to further outpatient treatment after 10-days hospitalization.